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Navigating the world of hormone replacement therapy (HRT) can be daunting, especially with the rise of bioidentical hormone therapy (BHT). Proponents claim BHT offers a more 'natural' and safer alternative to traditional HRT. But what does the science say? Let's delve into the realities, the hype, and the effective options available. 

Understanding Bioidentical Hormones

Bioidentical hormones are compounds chemically identical to those produced by the human body. They are often marketed as a natural solution for menopausal symptoms and other hormonal imbalances. However, the term 'bioidentical' is not recognized by the U.S. Food and Drug Administration (FDA), which states there is no scientific evidence that these hormones are identical to their naturally occurring counterparts. 

FDA-Approved vs. Compounded Bioidentical Hormones

Bioidentical hormones can be found in both FDA-approved pharmaceutical products and compounded preparations. FDA-approved bioidentical hormones have undergone rigorous testing for safety and efficacy. In contrast, compounded bioidentical hormones are custom-made by pharmacies and lack standardization and regulatory oversight. This absence of regulation raises concerns about their safety, purity, and effectiveness.  

The Endocrine Society's Position

The Endocrine Society has issued a position statement indicating that bioidentical hormones carry essentially the same risks and benefits as non-bioidentical hormones. They emphasize that there is no scientific evidence supporting claims that compounded bioidentical hormones are safer or more effective than FDA-approved formulations.  

Risks Associated with Compounded Hormones

Compounded bioidentical hormones are not subject to the same stringent quality control measures as FDA-approved medications. This lack of oversight can lead to inconsistencies in dosing and potential contamination, posing health risks to patients. The FDA has warned several pharmacies about making unsubstantiated claims regarding the safety and effectiveness of compounded hormone products.  

Making an Informed Decision

When considering hormone therapy:

  • Consult a Healthcare Professional: Discuss your symptoms and treatment options with a licensed healthcare provider.
  • Understand the Risks and Benefits: Recognize that all hormone therapies, bioidentical or not, carry potential risks and benefits.
  • Opt for FDA-Approved Treatments: Whenever possible, choose FDA-approved hormone therapies to ensure safety and efficacy.

At Prisk Orthopaedics & Wellness, we prioritize evidence-based treatments tailored to your individual needs. Our team is committed to providing safe and effective hormone replacement therapies that align with the latest medical guidelines.

Book a consultation today to explore your options for safe, evidence-based hormone replacement therapy.

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  2. Endocrine Society. (2006). Bioidentical Hormones: Position Statement. Retrieved from endocrine.org+1my.clevelandclinic.org+1
  3. American College of Obstetricians and Gynecologists. (2023). Compounded Bioidentical Menopausal Hormone Therapy. Retrieved from acog.org
  4. U.S. Food and Drug Administration. (2020). National Academies of Science, Engineering, and Medicine (NASEM) Study on the Clinical Utility of Treating Patients with Compounded “Bioidentical” Hormone Therapy. Retrieved from fda.gov+1Verywell Health+1
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